Recombinant Human Apoptosis Regulator Bcl-2, His 在 E. coli 中表達(dá)，N 端帶有一個(gè) His 標(biāo)簽。Bcl-2 家族的蛋白是胚胎和成年后許多組織中重要的細(xì)胞凋亡調(diào)節(jié)因子。
Synonyms
rHuApoptosis Regulator Bcl-2, His; B-cell Lymphoma 2; Apoptosis Regulator Bcl-2
Species
HumanSource
E. coli Accession
P10415 Gene ID
596 Molecular Weight
23-27 kDa AA Sequence
MAHAGRTGYD NREIVMKYIH YKLSQRGYEW DAGDVGAAPP GAAPAPGIFS SQPGHTPHPA ASRDPVARTS PLQTPAAPGA AAGPALSPVP PVVHLTLRQA GDDFSRRYRR DFAEMSSQLH LTPFTARGRF ATVVEELFRD GVNWGRIVAF FEFGGVMCVE SVNREMSPLV DNIALWMTEY LNRHLHTWIQ DNGGWDAFVE LYGPSMRPLF DHHHHHH Biological Activity
Data is not available. Appearance
Solution Formulation
Supplied as a 0.2 μm filter solution of 20 mM HEPES, 150 mM NaCl, 10% Glycerol, pH 7.4. Endotoxin Level
<1 EU/μg, determined by LAL method. Reconstitution
N/A Storage & Stability
Recombinant Human Apoptosis Regulator Bcl-2, His (rHuApoptosis Regulator Bcl-2, His) is stored at -20°C. It is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Shipping with dry ice. Background
Key regulators include proteins of the Bcl-2 family, some of which (e.g., Bcl-2, Bcl-xL, Mcl-1, and A1) promote cell survival while others (e.g., Bax and Bak) antagonize it. Disrupted regulation of apoptosis is implicated strongly in cancer and in autoimmune and degenerative diseases[1]. |
