Recombinant Human Fibroblast Growth Factor 8e 是 FGF-8 的亞型，F(xiàn)GF-8 是胚胎發(fā)育過程中的一個(gè)重要因子，參與前列腺癌的進(jìn)展。
Synonyms
rHuFGF-8e; AIGF; HBGF-8 ; 重組人成纖維細(xì)胞生長(zhǎng)因子 8e
Species
HumanSource
E. coli Accession
P55075 Gene ID
2253 Molecular Weight
Approximately 24.3 kDa AA Sequence
MQEGPGRGPA LGRELASLFR AGREPQGVSQ QHVREQSLVT DQLSRRLIRT YQLYSRTSGK HVQVLANKRI NAMAEDGDPF AKLIVETDTF GSRVRVRGAE TGLYICMNKK GKLIAKSNGK GKDCVFTEIV LENNYTALQN AKYEGWYMAF TRKGRPRKGS KTRQHQREVH FMKRLPRGHH TTEQSLRFEF LNYPPFTRSL RGSQRTWAPE PR Biological Activity
The ED50 is <2.5 μg/mL as measured by 3T3 cells. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human Fibroblast Growth Factor 8e (rHuFGF-8e) to 100 μg/mL using ddH2O or diluted with PBS. Storage & Stability
Lyophilized recombinant Human Fibroblast Growth Factor 8e (rHuFGF-8e) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Fibroblast Growth Factor 8 is an essential factor during embryonic development, overexpressed in several tumor types. Fibroblast Growth Factor 8 stimulates anti-apoptotic pathways and prevents tumor cell death[1]. |
