Recombinant Human Trefoil Factor-3 是一種參與胃腸道黏膜保護(hù)和修復(fù)的調(diào)節(jié)肽。
Synonyms
rHuTFF-3; ITF; TFI ; 重組人三葉肽因子3
Species
HumanSource
E. coli Accession
Q07654 Gene ID
7033 Molecular Weight
Approximately 6.6 kDa AA Sequence
EEYVGLSANQ CAVPAKDRVD CGYPHVTPKE CNNRGCCFDS RIPGVPWCFK PLQEAECTF Biological Activity
The ED50 is <10 μg/mL as measured by human MCF-7 cells, corresponding to a specific activity of >100 units/mg. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS, pH 7.4. Endotoxin Level
<1 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human Trefoil Factor-3 (rHuTFF-3) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA. Storage & Stability
Lyophilized recombinant Human Trefoil Factor-3 (rHuTFF-3) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Human Trefoil Factor-3 is a regulatory peptide involved in mucosal protection and repair in the gastrointestinal tract. TFF3 is predominantly present in the mucous cells of the small and large intestine. TFF3 also has potential therapeutic role of in NEC[1]. |
