Recombinant Mouse Platelet-Derived Growth Factor-AA 是 PDGF 家族成員，與 FDGFR 結(jié)合，具有增強(qiáng)骨愈合的潛力。
Synonyms
rMuPDGF-AA; PDGF-1; Pdgfa ; 重組小鼠血小板衍生生長(zhǎng)因子-AA
Species
MouseSource
E. coli Accession
P20033 Gene ID
18590 Molecular Weight
Approximately 28.7 kDa AA Sequence
MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATSNLN PDHREEETGR RRESGKNRKR KRLKPT Biological Activity
The ED50 is <50 ng/mL as measured by 3T3 cells. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against 1× PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Mouse Platelet-Derived Growth Factor-AA (rMuPDGF-AA) to 100 μg/mL using ddH2O. Storage & Stability
Lyophilized recombinant Mouse Platelet-Derived Growth Factor-AA (rMuPDGF-AA) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Platelet-Derived Growth Factor-AA is a member of PDGF family, which promotes cell proliferation, survival and migration, through binding to the tyrosine kinase PDGF receptor[1]. PDGF-AA may play a crucial role in the ability of ASCs and EPCs to enhance wound healing, especially in animal models with wound-healing deficits[2]. |
