Recombinant Mouse Macrophage Inflammatory Protein-2/CXCL2 是一種 CXC 趨化因子，能夠?qū)⒅行粤＜?xì)胞招募到感染部位。
Synonyms
rMuMIP-2/CXCL2; C-X-C motif chemokine 2; SCYB2 ; 重組小鼠巨噬細(xì)胞炎性蛋白-2/CXCL2
Species
MouseSource
E. coli Accession
P10889 Gene ID
20310 Molecular Weight
Approximately 8.0 kDa AA Sequence
GAVVASELRC QCLKTLPRVD FKNIQSLSVT PPGPHCAQTE VIATLKGGQK VCLDPEAPLV QKIIQKILNK GKAN Biological Activity
The EC50 is <1 ng/mL as measured by CHO-K1/Gα15/mCXCR2 cells (human Gα15 and mouse CXCR2 stably expressed in CHO-K1 cells). Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Mouse Macrophage Inflammatory Protein-2/CXCL2 (rMuMIP-2/CXCL2) to 100 μg/mL using ddH2O or PBS. Storage & Stability
Lyophilized recombinant Mouse Macrophage Inflammatory Protein-2/CXCL2 (rMuMIP-2/CXCL2) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
MIP-2, a member of the CXC chemokine family, is a peptide derived from monocytes/macrophages, and can recruit neutrophils to infection sites. MIP-2 release has an important impact on the development of early immune responses. MIP-2 is mainly produced by macrophages, one of the most dominant and widely distributed inflammatory cells, and is involved in the initiation and maintenance of the acute inflammatory response[1]. |
