Recombinant Rat GRO alpha/CXCL1 在炎癥、血管生成、腫瘤發(fā)生和傷口愈合中起重要作用。
Synonyms
rRtGRO-α/CXCL1; Growth-regulated alpha protein; C-X-C motif chemokine 1; CINC-1 ; 重組大鼠CXC 趨化因子1
Species
RatSource
E. coli Accession
P14095 Gene ID
81503 Molecular Weight
Approximately 7.8 kDa AA Sequence
APVANELRCQ CLQTVAGIHF KNIQSLKVMP PGPHCTQTEV IATLKNGREA CLDPEAPMVQ KIVQKMLKGV PK Biological Activity
Full biological activity determined by a chemotaxis bioassay using rat neutrophils is in a concentration range of 10-100 ng/ml. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against 20 mM PB, pH 7.4, 150 mM NaCl. Endotoxin Level
<1 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Rat GRO alpha/CXCL1 (rRtGRO-α/CXCL1) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA. Storage & Stability
Lyophilized recombinant Rat GRO alpha/CXCL1 (rRtGRO-α/CXCL1) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
CXCL1 plays a major role in inflammation, angiogenesis, tumorigenesis, and wound healing. CXCL1 is shown to be up-regulated in melanoma cells, and it is involved in pathogenesis of melanoma[1]. |
