Recombinant Mouse Fibroblast Growth Factor-7是一種有效的有絲分裂原，可促進包括皮膚、腸、乳腺、肝臟和肺在內(nèi)的各種器官的細胞增殖。
Synonyms
rMuFGF-7; HBGF-7; KGF ; 重組小鼠成纖維細胞生長因子-7
Species
MouseSource
E. coli Accession
P36363 Gene ID
14178 Molecular Weight
Approximately 18.7 kDa AA Sequence
CNDMSPEQTA TSVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNSYNIMEIR TVAVGIVAIK GVESEYYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHSGG EMFVALNQKG IPVKGKKTKK EQKTAHFLPM AIT Biological Activity
The ED50 is <2 ng/mL as measured by 4MBr-5 cells, corresponding to a specific activity of >5.0 × 105 units/mg. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Mouse Fibroblast Growth Factor-7 (rMuFGF-7) to 100 μg/mL using PBS. Storage & Stability
Lyophilized recombinant Mouse Fibroblast Growth Factor-7 (rMuFGF-7) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Fibroblast growth factor-7 (FGF-7) is a potent mitogen that enhances cell proliferation in various organs, including the skin, intestine, breast, liver, and lung[1]. FGF-7, also known as keratinocyte growth factor, insofar as it displays a unique cell specificity. FGF7 binds to perlecan protein core and that exogenous perlecan efficiently reconstitutes FGF7 mitogenic activity in perlecan-deficient cells[2].
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