Recombinant Human Fibroblast Growth Factor-6是成纖維細(xì)胞、血管內(nèi)皮細(xì)胞和前列腺癌細(xì)胞的一種有絲分裂原。
Synonyms
rHuFGF-6; HBGF-6; HST-2; HSTF-2 ; 重組人成纖維細(xì)胞生長因子-6
Species
HumanSource
E. coli Accession
P10767 Gene ID
2251 Molecular Weight
Approximately 18.8 kDa AA Sequence
MGTRANNTLL DSRGWGTLLS RSRAGLAGEI AGVNWESGYL VGIKRQRRLY CNVGIGFHLQ VLPDGRISGT HEENPYSLLE ISTVERGVVS LFGVRSALFV AMNSKGRLYA TPSFQEECKF RETLLPNNYN AYESDLYQGT YIALSKYGRV KRGSKVSPIM TVTHFLPRI Biological Activity
The ED50 is <2.5 ng/mL as measured by 3T3 cells, corresponding to a specific activity of >4.0 × 105 units/mg. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human Fibroblast Growth Factor-6 (rHuFGF-6) to 100 μg/mL using ddH2O. Storage & Stability
Lyophilized recombinant Human Fibroblast Growth Factor-6 (rHuFGF-6) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Fibroblast growth factor 6 (FGF-6) is a heparin-binding member of the FGF family, which are regulators of cell proliferation, differentiation, and function. FGF-6 binds and signals through the FGF receptors 1c, 2c, and 4[1]. FGF-6 is a potent mitogen for fibroblasts, vascular endothelial cells, and prostate carcinoma cells[2]. |
