Recombinant Rat Epidermal Growth Factor 是一種有效的表皮生長因子,能夠促進(jìn)上皮細(xì)胞增殖和遷移,能夠加快表皮傷口愈合,縮短治療時(shí)間。 Synonyms rRtEGF; Pro-epidermal growth factor; Urogastrone ; 重組大鼠表皮生長因子 Species RatSource E. coli Accession P07522 Gene ID 25313 Molecular Weight Approximately 6.3 kDa AA Sequence MNSNTGCPPS YDGYCLNGGV CMYVESVDRY VCNCVIGYIG ERCQHRDLRW WKLR Biological Activity The ED50 is <0.08 ng/mL as measured by 3T3 cells, corresponding to a specific activity of >1.25 × 107 units/mg. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Rat Epidermal Growth Factor (rRtEGF) to 100 μg/mL using ddH2O. Storage & Stability Lyophilized recombinant Rat Epidermal Growth Factor (rRtEGF) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Epidermal Growth Factor is secreted by epithelial cells, promotes epithelial proliferation and migration in a variety of tissues, and increases epithelial wound closure and shortens healing time[1]. Epidermal Growth Factor plays a key role in skin development and homeostasis, shows a protective function in the epidermal barrier. Epidermal Growth Factor also displays an immunomodulatory activity in the inflamed skin tissue[2]. |