Recombinant Mouse Acidic Fibroblast Growth Factor是由FGF1基因編碼的生長因子和信號蛋白。
Synonyms
rMuaFGF; HBGF-1; FGF1; FGF-a; FGF-acidic
Species
MouseSource
E. coli Accession
P61148 Gene ID
14164 Molecular Weight
Approximately 15.8 kDa AA Sequence
FNLPLGNYKK PKLLYCSNGG HFLRILPDGT VDGTRDRSDQ HIQLQLSAES AGEVYIKGTE TGQYLAMDTE GLLYGSQTPN EECLFLERLE ENHYNTYTSK KHAEKNWFVG LKKNGSCKRG PRTHYGQKAI LFLPLPVSSD Biological Activity
The ED50 is <0.4 ng/mL as measured by 3T3 cells, corresponding to a specific activity of >2.5 × 106 units/mg. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Murine Acidic Fibroblast Growth Factor (rMuaFGF) to 100 μg/mL using ddH2O. Storage & Stability
Lyophilized recombinant Murine Acidic Fibroblast Growth Factor (rMuaFGF) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Acidic Fibroblast Growth Factor is involved in a wide spectrum of biological functions including tissue development and repair, angiogenesis, proliferation of both epithelial and mesenchymal cells, and tumorigenesis. The biological activities of Acidic Fibroblast Growth Factor depend on binding to highly specific cell surface receptors, among which, fibroblast growth factor receptor 4 (FGFR4) is highly specific[1]. |
