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貨號 | 品名 | 規(guī)格 | 包裝 | 單價 | 貨期 | 庫存 |
JD1227177841 | GNB2 | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
性狀: | 【反應(yīng)特異性】Human , Mouse , Rat 【克隆 ID】EPR3261Y 【用途】WB , ICC 【抗原分子量】35kDa |
質(zhì)量標(biāo)準(zhǔn): | 【產(chǎn)品介紹】Guanine nucleotide binding protein beta-2 (GNB2) is a G-protein subunit belonging to WD repeat G protein beta family. GNB2 functions as a modulator or transducer for trans-membrane signaling pathway systems. G-protein is composed of alpha, beta, and gamma subunits, where beta and gamma subunits are required for GTPase activity and G-protein effector interaction (1). Specifically, GNB2 interacts with the glucocorticoid and migrates into the nucleus to suppress GR-induced trans-activation of the glucocorticoid-responsive genes (2). GNB2 has been identified as a binding partner to Ataxin 10, an important target in SCA10 disorder, and also a partner in regulating NTE, a protein known to cause delayed neuropathy with degeneration of nerve axon (3, 4).
WB, ICC WB: 1:1,000 - 10,000 Human, Mouse, Rat *Cross reactivity determined by western blot only. Products Data A. Western blot analysis on A) SH-SY5Y, B) Jurkat, Specificity A peptide corresponding to residues near N-term of |
貯存: | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), |