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| 貨號(hào) | 品名 | 規(guī)格 | 包裝 | 單價(jià) | 貨期 | 庫(kù)存 |
| JD1227177807 | FOXO4 Phospho (pS262) | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
| 性狀： | 【反應(yīng)特異性】Human 【克隆 ID】EPR2315(2) 【用途】WB 【抗原分子量】65kDa |
| 質(zhì)量標(biāo)準(zhǔn)： | 【產(chǎn)品介紹】FOXO4 is a member of the O class of winged helix/forkhead transcription factor family. It is regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this protein on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia (1). A constitutively active FOXO4 mutant where phosphorylation sites Thr-32, Ser-187 and Ser-262 have been mutated to alanine may have therapeutic potential in ERBB2/HER2-overexpressing cancers as it inhibits ERBB2-mediated cell survival, transformation and tumorigenicity (2).
WB WB: 1:10,000 - 50,000 Human *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on 293T cell lysates Specificity A phospho specific peptide corresponding to |
| 貯存： | Storage Condition and Buffer Store at -20° C. Buffer: PBS (pH 7.2), 0.01% sodium |
