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| 貨號 | 品名 | 規(guī)格 | 包裝 | 單價(jià) | 貨期 | 庫存 |
| JD1227177791 | FGR | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
| 性狀： | 【反應(yīng)特異性】Human 【克隆 ID】EPR3171 【用途】WB , ICC 【抗原分子量】56kDa |
| 質(zhì)量標(biāo)準(zhǔn)： | 【產(chǎn)品介紹】Fgr (c-fgr) is a member of the Src family of non-receptor protein-tyrosine kinases (PTK’s), which are involved in the intracellular signal transduction for growth and differentiation of the cells. Fgr consists of divergent N-terminal region which is involved in myristylation and palmitylation, conserved SH2 and SH3 internal domain involved in mediating protein-to- protein interactions with phosphotyrosine-containing and proline-rich motifs, and highly conserved C-terminal region tyrosine kinase catalytic domain. Fgr is commonly expressed in cells with hematopoietic origin (e.g. Myeloid cells, NK cells, B cells). Localized in the plasma membrane ruffles, Fgr functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Overexpression of Fgr is seen as a result of Epstein-Barr Virus (EBV) infection (4).
WB, ICC WB: 1:1,000 - 10,000 Human *Species cross-reactivity is based on WB analysis Products Data Western blot analysis on Raji cell lysate using Specificity A synthetic peptide corresponding to C-terminus of human |
| 貯存： | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), |
