4007787550
|
 |
||||||||||||||
| 貨號 | 品名 | 規(guī)格 | 包裝 | 單價 | 貨期 | 庫存 |
| JD1227177789 | Fes (FES) | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
| 性狀： | 【反應(yīng)特異性】Human , Mouse 【克隆 ID】EPR3229 【用途】WB , ICC 【抗原分子量】93kDa |
| 質(zhì)量標(biāo)準(zhǔn)： | 【產(chǎn)品介紹】Fes (c-Fes) is a non-receptor protein- tyrosine kinase implicated in myeloid, vascular endothelial and neuronal cell differentiation. Closely related to Fer, Fes is characterized by a unique amino-terminal region (critical for kinase regulation and downstream signaling), a central SH2 domain, and a carboxyl-terminal kinase domain (1, 2). Fes lacks an SH3 domain, a negative regulatory tail, and other features that contribute to negative regulation of c-Src, c-Abl, and other cytoplasmic tyrosine kinases. Fes activation in response to growth factors and cytokines has been linked to various cellular events including survival, proliferation, differentiation, and reorganization of the cytoskeleton. Fes has been implicated as a tumor suppressor in colorectal cancer (3).
WB, ICC WB: 1:1,000 - 5,000 Human, Mouse *Cross reactivity determined by western blot only. Products Data Western blot analysis on A) TF-1, B) fetal kidney, Specificity A synthetic peptide corresponding to residues near |
| 貯存： | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), |
