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【產品介紹】Ferritin is an iron-sequestering protein
that specifically localizes in the mitochondria (1).
It stores iron in a soluble, non-toxic, readily
available form; thus, it is important for iron
homeostasis and has ferroxidase activity (2). Ferritin
is different from cytosolic ferritins; ferritin is
not ubiquitous and not found in cultured cells such as
HeLa or H1299. It is highly expressed in the
testis, particularly in spermatocytes and Leydig cells,
and it is also found in the heart, nervous system,
pancreas (islet of Langerhans) and kidney, but only in
cells characterized by high metabolic activity.
Furthermore, ferritin is important in reducing the
harmful interaction between Fe and H2O2, which may
be particularly dangerous in cells with
sustained respiratory activity (1).

Recommended Applications

WB
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
Species Reactivity *

Human

*Species cross-reactivity is based on WB analysis

Products Data

Western blot analysis on human testis lysate
using anti-Ferritin, mitochondrial RabMAb (cat. #3832-1).

Specificity

A synthetic peptide corresponding to residues in
the C-terminus of human Ferritin, mitochondrial was used
as an immunogen.

貯存：

Storage Condition and Buffer

Store at -20° C. 50 mM Tris-Glycine (pH 7.4),
0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and
0.05% BSA. Stable for 12 months from date of receipt.

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