4007787550
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| 貨號 | 品名 | 規(guī)格 | 包裝 | 單價 | 貨期 | 庫存 |
| JD1227177772 | Ezrin Rabbit Antibody | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
| 性狀： | 【反應特異性】Human , Mouse , Rat 【克隆 ID】EP924Y 【用途】WB , ICC , FC 【抗原分子量】81 kDa |
| 質(zhì)量標準： | 【產(chǎn)品介紹】Erzin, a member of the Ezrin, Radixin, Moesin (ERM) family, is a linker protein located between cell surface recept o r s, adhesion molecules, a n d actin cytoskeleton (1-2). Ezrin activity is regulated by intramolecular interactions between N- a n d C-terminal ERM association domains (3). Erzin tyrosine phosph o r ylation can also be induced by EGF, PDGF a n d HGF stimulation. Erzin interacts with PI3-K protein kinase A a n d Rho (4). In response to epidermal growth fact o r (EGF) the microvillar c o r e protein ezrin is phosph o r ylated transiently to a high level on tyrosine residues in human epidermoid carcinoma A431 cells. Tyr145, lies in the N-terminal region of homology that is common to the b a n d 4.1-talin-ezrin protein family. This tyrosine residue a n d its vicinal amino acids are conserved throughout the family members, including radixin, moesin, a n d the two phosphotyrosine phosphatases, PTP H1 a n d PTP MEG, but not in b a n d 4.1 o r talin (5).
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