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| 貨號(hào) | 品名 | 規(guī)格 | 包裝 | 單價(jià) | 貨期 | 庫存 |
| JD1227177747 | eIF-3E (EIF3E) | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
| 性狀： | 【反應(yīng)特異性】Human , Mouse , Rat 【克隆 ID】EPR6877 【用途】WB , ICC 【抗原分子量】48kDa |
| 質(zhì)量標(biāo)準(zhǔn)： | 【產(chǎn)品介紹】eIF-3E is the p48 subunit of the translational initiation factor eIF3. It forms a multi-factor complex with eIF1, eIF5, and the eIF2-GTP-Met-tRNA ternary complex that binds to the 40S ribosomal subunit to form the 43S preinitiation complex (PIC). eIF-3E also prevents the premature joining of the 60S ribosomal subunit until the start codon is recognized. In addition, eIF-3E plays a role in recruiting eIF4G-associated mRNAs to the 43S PIC to form the 48S PIC and initiate mRNA scanning (1). It is required for nonsense-mediated mRNA decay (NMD) and acts in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. eIF-3E also interacts with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins (2).
WB, ICC WB: 1:1,000 - 10,000 Human, Mouse, Rat *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) Jurkat, (B) 293T, Specificity A synthetic peptide corresponding to residues in |
| 貯存： | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, |
