4007787550
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| 貨號 | 品名 | 規(guī)格 | 包裝 | 單價 | 貨期 | 庫存 |
| JD1227177741 | eEF-2K (C-term) | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
| 性狀： | 【反應(yīng)特異性】Human , Mouse , Rat 【克隆 ID】EP881Y 【用途】WB , ICC , IP 【抗原分子量】95 kDa |
| 質(zhì)量標(biāo)準(zhǔn)： | 【產(chǎn)品介紹】Eukaryotic elongation fact o r -2 kinase (eEF-2k) previously known as Ca2+/ calmodulin-dependent protein kinase III, is an abundant cytoplasmic protein highly specific f o r elongation fact o r -2 (eEf-2) (1). Phosph o r ylation of eEF-2 by eEF-2 kinase on specific threonine residues results in the inactivation of eEF-2 a n d in termination of mRNA translation (2). The activity of eEF2 kinase is not only dependent upon Ca2+ ions, calmodulin (CaM) a n d insulin, but is also regulated both negatively a n d positively via phosph o r ylation by different protein kinases (AMPK, S6K1, p90 RSK) (3-4). There is also evidence that eEF-2 phosph o r ylation is involved in the regulation of cell cycle progression, cellular differentiation, oogensis a n d malignant tum o r s (5-6).
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