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貨號 | 品名 | 規(guī)格 | 包裝 | 單價 | 貨期 | 庫存 |
JD1227177668 | CrkL Phospho(pY207) | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
性狀: | 【反應(yīng)特異性】Human , Mouse 【克隆 ID】EP270Y 【用途】WB , IP 【抗原分子量】39 kDa |
質(zhì)量標準: | 【產(chǎn)品介紹】CrkL (Crk-like), a 36kDa protein predominantly expressed in hematopoietic cell lines, is a member of the Crk adapter protein family. Lacking any intrinsic enzymatic activity, CrkL is composed of one SH2 domain a n d two SH3 domains (1). The SH2 domain of CrkL as been shown to interact with c-Cbl, Cas, Hef-1 a n d Paxillin (2); while the N-terminal SH3 can bind to c-ABL, Sos1 a n d C3G (3). Additionally, the phosph o r ylated f o r m of CrkL (pY207) binds to BCr-ABL oncogene in chronic myelogenous leukemia cells (4).
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