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| 貨號 | 品名 | 規(guī)格 | 包裝 | 單價 | 貨期 | 庫存 |
| JD1227177667 | Crk/p38 (CRK) | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
| 性狀： | 【反應特異性】Human , Mouse , Rat 【克隆 ID】EPR4984(2) 【用途】WB , ICC , FC , IP 【抗原分子量】38kDa |
| 質量標準： | 【產品介紹】Crk (p38) are adaptor proteins, composed mostly of SH2 and SH3 domains, which play a key role in cellular signaling by mediating the construction of protein complexes and also by managing cell proliferation, differentiation, and migration (1). They are critical integrators of upstream signals for cell invasion and migration in human cancer cell lines. Crk is believed to be a regulator of invasive responses because increased levels of the protein have been observed in multiple human cancers (2). In vivo studies have demonstrated that decreased levels of Crk remarkably inhibits tumor formation and its invasive growth (3). Crk associates with ERM family proteins (including ezrin, radixin, and moesin), activates RhoA, and promotes cell motility toward hyaluronic acid (4).
WB, ICC, IP, FC WB: 1:1,000 - 10,000 Human, Mouse, Rat *Species cross-reactivity is based on WB analysis. Products Data Specificity A synthetic peptide corresponding to residues in human Crk/p38 was used as an immunogen. |
| 貯存： | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, |
