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貨號 | 品名 | 規(guī)格 | 包裝 | 單價 | 貨期 | 庫存 |
JD1227177657 | c-Myc DyLight? 488 (MYC) | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
性狀: | 【反應(yīng)特異性】Human 【克隆 ID】Y69 【用途】ICC 【抗原分子量】57kDa |
質(zhì)量標準: | 【產(chǎn)品介紹】Oncogene-encoded proteins c-Myc, N-Myc, and L-Myc function in cell proliferation, differentiation and neoplastic disease. Amplification of the c-Myc gene has been found in several types of human tumors, the N-Myc gene in neuroblastomas (1), and the L-Myc gene in human small cell lung carcinomas (2). c-Myc protein is a transcription factor localized to the nucleus of the cell. It seems to be involved in activating the transcription of growth-related genes. c-Myc binds to DNA during transcription as a heterodimeric complex with Max. c-Myc is phosphorylated in vitro by p44/42 MAP kinase at Ser62 (3) and in vivo at both Thr58 and Ser62. Mutation of Thr58 and Ser62 to Ala inhibits the ability of c-Myc to activate transcription (3).
ICC ICC: 1:50 - 100 Human Products Data Immunofluorescent staining of HeLa cells using Specificity A synthetic peptide corresponding to residues in |
貯存: | Storage Condition and Buffer Store at 2-8° C. PBS (pH 7.2), 0.02% sodium azide, |