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貨號(hào) | 品名 | 規(guī)格 | 包裝 | 單價(jià) | 貨期 | 庫(kù)存 |
JD1227177643 | CEACAM1 | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
性狀: | 【反應(yīng)特異性】Human 【克隆 ID】EPR4048 【用途】WB , IHC 【抗原分子量】120-180kDa |
質(zhì)量標(biāo)準(zhǔn): | 【產(chǎn)品介紹】Carcinoembryonic antigen-related cell adhesion molecule (CEACAM) proteins, members of the immunoglobulin (Ig) superfamily, are involved in cell-cell recognition and modulate cellular processes that range from the shaping of tissue architecture and neovascularization to the regulation of insulin homeostasis and T-cell proliferation (1). CEACAM1 is a type I membrane glycoprotein that plays a role in intercellular adhesion to inhibit tumor development as a bacterial adhesin (2). Moreover, CEACAM1 is an active regulator of cell signaling by modulating the insulin or EGF receptor pathways in epithelial cells or the Zap-70 pathway in hematopoietic cells (2). It is known to be a tumor suppressor, since CEACAM1 is down-regulated in most epithelial cell cancers and T-cell leukemias (3).
WB, IHC WB: 1:1,000-10,000 Human
Western blot analysis on (A) HepG2, (B) fetal liver, Immunohistochemical staining of paraffin-embedded Immunohistochemical staining of paraffin-embedded
A synthetic peptide corresponding to residues near |
貯存: | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), |