|
![]() |
貨號(hào) | 品名 | 規(guī)格 | 包裝 | 單價(jià) | 貨期 | 庫(kù)存 |
JD1227177604 | Caveolin 2 Phospho (pY19) (CAV2) | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
性狀: | 【反應(yīng)特異性】Human 【克隆 ID】EPR2220(3) 【用途】WB , FC 【抗原分子量】20kDa |
質(zhì)量標(biāo)準(zhǔn): | 【產(chǎn)品介紹】Caveolins (Caveolin 1, 2, and 3) are a family of caveolae-associated integral membrane proteins. Caveolae are cholesterol/sphingolipid-rich microdomains of the plasma membrane that have been implicated in signal transduction and vesicular trafficking (1). Caveolin 2 is a principal component of caveolae membranes. It interacts directly with heterotrimeric guanine nucleotide binding proteins (G proteins) and can functionally regulate their activity. Caveolins 1 and 2 are similar in most respects; however, they differ in their functional interactions with heterotrimeric G proteins, possibly explaining why Caveolin-1 and -2 are coexpressed within a single cell (2). Caveolin-2 is up-regulated in response to the mechanical injury of differentiated PC12 cells, which is strictly dependent on continued treatment with NGF. Both Caveolin-1 and -2 are more abundantly expressed in white adipose tissue and are induced during adipocyte differentiation. Robust expression of Caveolin-1 and -2 is also observed along the entire cell surface of DRG neurons, including high levels on growth cones (1). Phosphorylation on Tyr-19 is required for insulin-induced phosphorylation of MAPK1 and DNA binding of STAT3 (2).
WB, FC WB: 1:1,000 - 10,000 Human *Species cross-reactivity is based on WB analysis.
Western blot analysis on HUVEC cell lysates
A phospho specific peptide corresponding to |
貯存: | Storage Condition and Buffer Store at -20° C. Buffer: 50 mM Tris-Glycine (pH 7.4), |