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| 貨號(hào) | 品名 | 規(guī)格 | 包裝 | 單價(jià) | 貨期 | 庫(kù)存 |
| JD1227177588 | Caldesmon Phospho (pT753) (CALD1) | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
| 性狀： | 【反應(yīng)特異性】Human 【克隆 ID】EPR2211Y 【用途】WB , ICC 【抗原分子量】120-150 (smooth muscle)/70-80 |
| 質(zhì)量標(biāo)準(zhǔn)： | 【產(chǎn)品介紹】Caldesmon is a smooth muscle and nonmuscle regulatory protein that interacts with actin, myosin, tropomyosin, and calmodulin (1,2). Smooth muscle caldesmon is an elongated molecule with a calmodulin, tropomyosin, and actin-binding region at the C-terminus and a myosin-binding domain at the N-terminus (3). Caldesmon stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, caldesmon inhibits the actomyosin ATPase by binding to F-actin. This inhibition is reduced by calcium-calmodulin and is promoted by tropomyosin (4). Phosphorylation of non-muscle caldesmon has been linked to reduction of caldesmon's binding properties to actin, myosin, and calmodulin. Also, caldesmon's inhibition of actomyosin ATPase is reduced with its Phosphorylation (5).
WB, ICC WB: 1:1000 - 5000 Human Products Data Western blot analysis on HeLa cell lysates |
