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| 貨號(hào) | 品名 | 規(guī)格 | 包裝 | 單價(jià) | 貨期 | 庫(kù)存 |
| JD1227177573 | Bim | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
| 性狀： | 【反應(yīng)特異性】Human 【克隆 ID】Y36 【用途】WB , IHC , ICC , IP 【抗原分子量】22 kDa |
| 質(zhì)量標(biāo)準(zhǔn)： | 【產(chǎn)品介紹】Bim, Bcl-2 interacting mediat o r of cell death, is a pro-apoptotic protein belonging to the BH3-only group of Bcl-2 family members (1). Bim promotes apoptosis by binding to a n d inhibiting the activity of anti-apoptotic Bcl-2 family members, inducing the release of cytochrome c from mitochondria (2). Bim is sequestered in an inactive conf o r mation through binding to the microtubule-associated dynein mot o r complex. Certain apoptotic stimuli release Bim from microtubules, allowing inhibit o r y binding to anti-apoptotic Bcl-2 family members a n d subsequent iniation of apoptosis (3,4).
A. Western blot analysis on A431 cell lysate using B. Immunohistochemical analysis of paraffin-embedded |
