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貨號 | 品名 | 規(guī)格 | 包裝 | 單價 | 貨期 | 庫存 |
JD1227177560 | Bcl-2 Rabbit Antibody | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
性狀: | 【反應(yīng)特異性】Human , Mouse 【克隆 ID】E17 【用途】WB , IHC , ICC , FC , IP 【抗原分子量】26 kDa |
質(zhì)量標(biāo)準(zhǔn): | 【產(chǎn)品介紹】The Bcl-2 family of proteins regulate apoptosis by controlling mitochondrial permeability a n d release of cytochrome c. Bcl-2 is an anti-apoptotic protein that resides in the outer mitochondrial wall a n d inhibits release of cytochrome c (1). Over-expression of Bcl-2 has been shown to promote cell survival by suppressing apoptosis. It has been documented that bcl-2 becomes deregulated in tum o r cells as a result of translocation into the immunoglobulin heavy-chain locus a n d is theref o r e activated in B cell malignancies (2). It has also been shown that post-translational modification of Bcl-2, phosph o r ylation at serine 70, may be required to render its full a n d / o r enhanced anti-apoptotic effect (3, 4).
A. Western blot analysis of Jurkat cell lysate B. Immunohistochemical analysis of paraffin-embedded C. Flow cytometric analysis of permeabilized Jurkat |