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貨號 | 品名 | 規(guī)格 | 包裝 | 單價 | 貨期 | 庫存 |
JD1227177559 | Bcl-10 Rabbit Antibody | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
性狀: | 【反應(yīng)特異性】Human 【克隆 ID】EP605Y 【用途】WB , IHC , FC , IP 【抗原分子量】32 kDa |
質(zhì)量標(biāo)準(zhǔn): | 【產(chǎn)品介紹】Bcl-10 is an adapt o r protein with a caspase recruitment domain (CARD) that promotes apoptosis a n d activates pro-caspase 9 a n d NF-kB (1-2). Bcl-10 also interacts with other CARD domain containing proteins including CARD9, 10, 11 a n d 14. Bcl-10 is found to f o r m a complex with MALT1, a protein known to be translocated in MALT lymphomas. Bcl-10 a n d MALT1 play a critical role in antigen recept o r mediated lymphocyte proliferation a n d signaling to NF-B, which controls the expression of genes critical f o r cell survival, proliferation, a n d immune responses (3-4). Defects in Bcl-10 have been identified in various types of cancer.
A. Western blot analysis on Raji cell lysate B. Immunohistochemical analysis of paraffin-embedded |