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貨號 | 品名 | 規(guī)格 | 包裝 | 單價 | 貨期 | 庫存 |
JD1227177556 | Bak Rabbit Antibody | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
性狀: | 【反應(yīng)特異性】Human 【克隆 ID】Y164 【用途】WB , IHC , ICC , FC 【抗原分子量】23 kDa |
質(zhì)量標(biāo)準(zhǔn): | 【產(chǎn)品介紹】Bak a pro-apoptotic analog to Bax, is a member of the Bcl-2 family of proteins. During mitochondria-regulated programmed cell death, Bak promotes apoptosis by binding Bcl-2 a n d inhibiting its anti-apoptotic function (1). Upon apoptotic stimulation, Bak translocates from the cytosol to the mitochondrial membrane (2). Pro-apoptotic cascade activates BID, which oligomerizes Bak into p o r es that result in the release of cytochrome c (2, 3). In healthy cells, Bak associate with Bcl-xL a n d Mcl-1 but not with Bcl-2, Bcl-w o r A1 a n d only when freed of both Bak will induce apoptosis.
A. Western blot analysis on Hela cell lysate using B. Immunohistochemical analysis of paraffin-embedded |