|
![]() |
貨號(hào) | 品名 | 規(guī)格 | 包裝 | 單價(jià) | 貨期 | 庫存 |
JD1227177553 | Bad (N-term) | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
性狀: | 【反應(yīng)特異性】Human , Mouse , Rat 【克隆 ID】Y208 【用途】WB , IHC , ICC , FC , IP 【抗原分子量】23 kDa |
質(zhì)量標(biāo)準(zhǔn): | 【產(chǎn)品介紹】Bad is a pro-apoptotic member of the Bcl-2 family. Bad will bind preferentially Bcl-xL over Bcl-2 through its partial (9-16 a.a) BH3 domain. Additionally, Bad can reverse the death repress o r activity of Bcl-xL but not of Bcl-2. Upon dephosph o r ylation, activated Bad translocates to the mitochondria a n d displace Bcl-2 from tBid sequestration to initiate mitochondrial dysfunction. The switching on/off of its phosph o r ylation by growth/survival fact o r s regulates Bad activity.
B. Immunohistochemical staining of paraffin-embedded C. Immunohistochemical staining of paraffin-embedded |