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貨號(hào) | 品名 | 規(guī)格 | 包裝 | 單價(jià) | 貨期 | 庫(kù)存 |
JD1227177551 | B7-H2 (ICOSLG) | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
性狀: | 【反應(yīng)特異性】Human 【克隆 ID】EPR6071 【用途】WB , ICC 【抗原分子量】63 - 72kDa |
質(zhì)量標(biāo)準(zhǔn): | 【產(chǎn)品介紹】B7-H2, or Inducible costimulator ligand (ICOSL), is a member of the Ig superfamily and belongs to the B7 family of costimulatory molecules. It specifically binds to ICOS, but not to other T cell costimulatory molecules such as CD28 and CTLA-4. B7-H2-ICOS interaction appears to be very important in the expansion of activated T cells and late-phase immune responses (1). B7-H2 enhances the proliferation of both CD4 and CD8 T cells, the secretion of Th1- and/or Th2-type cytokines, and the expression of CD154 (CD40 ligand) on T cells (2). It is expressed constitutively on B lymphocytes and at low levels on monocytes (3). Furthermore, B7-H2-ICOS interaction induces IL-10 production, which plays an important role in reducing immune responses (4).
WB, ICC WB: 1:1,000 - 10,000 Human *Species cross-reactivity is based on WB analysis. Products Data Specificity A synthetic peptide corresponding to residues in |
貯存: | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, |